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The number of human trafficking cases in Missouri has nearly doubled in Missouri in the past five years, and advocates against trafficking are saying it's happening more often to kids because of the pandemic. 

Police said a man lost his temper and punched his 3-month-old baby, severely injuring the child in O'Fallon, Missouri.

St. Louis-based companies worry about their employees trapped in Ukraine.

Malcolm Mathis II, 33, and 22-month-old Malcolm Mathis III were found stabbed to death at their home. The slain father’s 4-year-old daughter and mother-in-law were badly injured during the gruesome attack but survived.

Authorities said a 63-year-old southwest Missouri man is charged with killing a man he thought had stolen from his property.

Less than two weeks ago, Missouri was on pace for a 71.2% drop in reported COVID-19 cases from January to February. On this final day of February, FOX 2 has counted a total of 51,380 confirmed COVID cases, a 79.9% drop from last month's tally of 255,880 cases

MARION, Ark.-- A Missouri man is facing charges after police say he held a mother and her baby hostage from St. Louis to Marion, Arkansas. According to the Marion Police Department, units responded to I-55 in reference to a kidnapping. The suspect, Julius Rogers, fled from police and initiated a high speed chase on I-55 [...]

A panel of experts and USA Today’s 10Best editors have selected the Saint Louis Science Center as one of the nominees for Best Science Museum in USA Today’s 10Best Reader’s Choice for 2022.

Two men have been charged in a shooting in southeast Missouri that left two women dead and 14 people injured.

Detectives with the St. Louis Metropolitan Police Department are asking for the public's help in locating a man accused of robbing two women at gunpoint during a home invasion.

The St. Louis region dropped to 254 total COVID hospitalizations this past weekend, the lowest reported number since July 10, 2021.

Harris-Stowe State University now has its first African American woman to serve as president of the university.

The Illinois State Police is cautioning drivers to beware of a planned trucker convoy that is expected to pass through the state this week to disrupt traffic.

JOPLIN, Mo. — Dozens of people came out Monday in Joplin to show support for "The People's Convoy" as it passed through town. Hundreds of vehicles from semis to trucks and even RV campers passed by cheering supporters with American flags and signs just before 10:00 AM on I-44. This convoy, along with many others, [...]

ST. LOUIS - A woman was shot while at the Pin-Up Bowl in the Delmar Loop late Sunday night. Police said shots were fired at 11:56 p.m. when an altercation started in the Pin-Up Bowl. It continued outside to the front of the business. The suspects then began shooting at each other. Then they entered [...]

Police say a teen was shot and killed inside a suburban St. Louis business over the weekend.

ST. LOUIS - A man was shot at a gas station in St. Louis City Monday morning. The shooting happened just before 6 a.m. in the 1600 block of Union Boulevard at the ZX Gas Station. The 31-year-old man was conscious and breathing when officers arrived at the scene. He was then taken to the [...]

ST. LOUIS - Monday starts the week off nicely. It will be sunny and warm with high temperatures in the upper-50s. High-pressure overhead will keep the quiet weather around for most of the week. Temperatures will be well above normal, mainly in the 60s. So far, the weekend forecast is looking wet.

ST. LOUIS - Car break-in suspects led police on a chase Sunday night, and it was caught on camera. Surveillance video showed four men breaking into cars at the La Quinta Inn on Lindbergh near I-44. At least five cars were hit. When Sunset Hills officers arrived at about 11:45 p.m., the men jumped into [...]

Beginning Monday, many parts of the St. Louis metropolitan area will no longer be under a mask mandate. The move comes as COVID-19 cases and hospitalizations are on the decline.