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A man was reported missing from DeSoto, Missouri, after his family said he never came home from work back in January

The 5th district officers decided to form a human ladder to rescue a mother and her daughter from a second-floor window.  

A national investigation is now descending on the St. Louis VA Medical Center after a patient died by suicide in the emergency room. FOX 2 first broke the story in September and has now learned how the unthinkable happened.

The American Red Cross is in critical

A mother of three was both angry and frustrated when her bathroom ceiling ended up on the floors of her apartment in north St. Louis.

Putin warned other countries that any attempt to interfere with the Russian action would lead to “consequences they have never seen.”

Nexstar's KXAN talked with University of Texas experts Wednesday to help address some of the questions we've been hearing surrounding that situation growing more tense at Ukraine's borders.

Retiring Republican Sen. Roy Blunt said, for now, he does not plan on endorsing a candidate to fill his seat in Washington D.C. 

Schnucks is voluntarily recalling certain packs of fresh ground beef sold at its Affton store because the product may contain pieces of plastic.

A St. Louis man was indicted by a federal grand jury for allegedly robbing multiple QuikTrip locations in December while armed with a semi-automatic pistol.

What started out as a normal Saturday, turned into a memorable one at Coachlite Skating Rink in Bridgeton thanks to St. Louis County police officers.

President Biden on Wednesday announced sanctions against a controversial Russian natural gas pipeline. 

Imagine being held in jail three weeks for a crime you didn't commit.

One month ago, more than 1,300 people were in area hospital beds for COVID treatment. As of Wednesday, Feb. 23, that number stands at just 346 people. Only 310 of those individuals are confirmed to be COVID positive. It’s a remarkable collapse of the omicron variant-fueled surge in the St. Louis area in such a short time.

Former Missouri U.S. Senator John Danforth has commissioned a poll showing a right-center candidate could win in November's general election.

The five-minute commute to work at the State Capitol from the Governor's Mansion was a little different for Governor Mike Parson Wednesday. Instead of a car or SUV, he traveled by a tractor. Parson has proclaimed this week as National FFA Week in Missouri in a ceremony at the Capitol Rotunda. The Governor took a [...]

ST. LOUIS – Another winter storm is headed for St. Louis Wednesday. It is supposed to impact road conditions Wednesday and Thursday. With extreme winter weather comes extreme road conditions. FOX 2 has a tool for motorists to check before heading out. Go to our website at fox2now.com and then click the traffic section. Once you are on [...]

Winter Storm Warnings and Advisories cover the entire area for this afternoon through Thursday.

ST. LOUIS---With the St. Louis region poised to enter a Winter Storm Warning from the National Weather Service starting at noon Wednesday, dozens of school districts in the FOX2 viewing area have decided to dismiss students early. You can find the complete list of closings here. Most of the districts are in the southern part [...]

The Ohio Valley Conference is crossing the Missouri River and expanding west, with Wednesday's announcement that Lindenwood University will petition the NCAA to move up to Division I and join the conference starting in the 2022-2023 academic year.